Botox, the wrinkle treatment made by Allergan, has been approved to treat adults with overactive bladders who cannot tolerate or were not helped by other drugs, the Food and Drug Administration said on Friday. Botox injected into the bladder muscle causes the bladder to relax, increasing its storage capacity. “Clinical studies have demonstrated Botox’s ability to significantly reduce the frequency of urinary incontinence,” Dr. Hylton V. Joffe, director of the F.D.A.’s reproductive and urologic products division, said in a statement. “Today’s approval provides an important additional treatment option for patients with overactive bladder, a condition that affects an estimated 33 million men and women in the United States.”
Officials will conduct an autopsy this morning on the body of a West Rogers Park man who was exhumed from Rosehill Cemetery on Chicago's North Side after dying of cyanide poisoning last summer after winning a million-dollar lottery.
A hearse was being opened in front of a green tent set up at the grave site just north of Peterson Avenue and Urooj Khan's body was loaded into it. An evidence technician snapped a photo of it before the hearse's rear doors were closed up and the vehicle began driving away across the grass on the cemetery, escorted by a Chicago police evidence technician squad car and several other marked and unmarked police vehicles. They exited west onto Peterson Avenue.
The whole exhumation process lasted about two hours.
Khan's body was not frozen, officials said, and his autopsy will be today. A medical examiner's office spokeswoman, Mary Paleologos, said Khan's body will be buried again on Monday.
Dr. Marta Helenowski, the forensic pathologist who originally handled Khan's case, will be performing the autopsy this morning at the medical examiner's office, 2121 W. Harrison St., Paleologos said in a telephone interview.
The pathologist is going to be taking samples of Khan's lungs, liver and spleen for further testing. She will also be looking at the contents of Khan's stomach and intestines and taking bone, nail and hair samples, all for further examination, according Paleologos.
"Depending on the condition of the body and the quality of the samples, (the medical examiner's office) will hopefully be able to determine how the cyanide entered his body," Paleologos said.
Chief Medical Examiner Stephen J. Cina will hold a 2:30 p.m. news conference about the autopsy. He will likely only be able to discuss whether Khan's body is in good condition and if the samples taken from it are good quality.
It'll be two or three weeks before the medical examiner's office knows how the cyanide got into Khan's system. The office will also have to wait for independent lab test results.
Helenowski and a few medical examiner's office personnel were on hand for the exhumation. An imam also was present to say prayers at the grave site as the exhumation went on.
Several helicopters hovered over Rosehill Cemetery this morning and a backhoe and three or four pickup trucks were stationed at the grave site in the middle of the cemetery's northern section, where a beam of light could be seen shining over Khan's headstone. The backhoe soon began its work digging into the ground at the grave site. In addition to the backhoe, one or two workers were seen helping dig up the body with shovels.
A large tent was set up at the site where some two dozen police officers were gathered. Among the officers are two Chicago police evidence technicians, Paleologos said. One was taking still photos of the exhumation, while the other was shooting video.
An unmarked police car and two blue barricades blocked off the Peterson Avenue gate to Rosehill, the only entrance and exit in the northern section of the cemetery.
Four TV trucks sat parked along the fence about 100 yards west of the grave site along Oakley Avenue, the designated staging area for the media. A group of about a dozen photographers, a videographer and TV reporters stood along the Peterson Avenue fence, next to where traffic moved along the busy thoroughfare like any normal morning rush hour.
A few passersby gazed at the police activity at the grave site from Oakley Avenue. One, curious about large presence inside the cemetery, was surprised to learned from a Tribune reporter that it was Khan's body being dug up. Another thought someone was having a funeral.
The exhumation of Khan's remains – scheduled to begin at about 7 a.m. – will come about six months after he was buried at Rosehill. In court papers last week, Cina said it was important to exhume the remains "as expeditiously as possible" since Khan's body was not embalmed.
In court papers, Cina said it was necessary to perform a full autopsy to "further confirm the results of the blood analysis as well as to rule out any other natural causes that might have contributed to or caused Mr. Khan's death."
The exhumation comes after the Tribune broke the story on Jan. 7 about Khan's mysterious death, sparking international media interest in the case.
The medical examiner's office initially ruled Khan's July 20 death was from hardening of the arteries when there were no signs of trauma on the body and a preliminary blood test didn't raise any questions. But the investigation was reopened about a week later after a relative suggested to authorities that Khan's death "may have been the result of poisoning," prosecutors said in a court filing seeking the exhumation.
The medical examiner's office contacted Chicago police Sept. 11 after tests showed cyanide in Khan's blood. By late November, more comprehensive toxicological tests showed lethal levels of the toxic chemical and the medical examiner's office declared his death a homicide.
Khan's widow, Shabana Ansari, who has hired a criminal-defense lawyer, told the Tribune last week that she had been questioned for more than four hours by detectives and had fully cooperated. She said the detectives had asked her about ingredients she used to prepare his last meal of lamb curry, shared by Ansari, her father-in-law Fareedun Ansari and Khan's daughter from a previous marriage, Jasmeen, 17.
While a motive has not been determined, police have not ruled out that Khan was killed because of his lottery win, a law enforcement source has told the Tribune. He died before he could collect the winnings – a lump-sum payment of about $425,000 after taxes.
According to court records obtained by the Tribune, Khan's brother has squabbled with Shabana Ansari over the lottery winnings in probate court. The brother, ImTiaz Khan, raised concern that since Khan left no will, Jasmeen Khan would not get "her fair share" of her father's estate.
Khan and Ansari did not have children together. Since her father's death, Jasmeen Khan has been living with Khan's siblings.
An attorney for Ansari in the probate case said the money was all accounted for and the estate was in the process of being divided up by the court. Under state law, the estate typically would be split evenly between the spouse and Khan's only child, he said.
In addition, almost two years ago, the Internal Revenue Service placed liens on Khan's residence on West Pratt Boulevard in an effort to collect more than $120,000 in back taxes from his father-in-law, Fareedun Ansari, who still lives at the home with his daughter.
Fareedun and Shabana Ansari have denied involvement in Khan's death.
jgorner@tribune.com
Twitter: @ChicagoBreaking
